Substrate: Nitric-oxide synthase, endothelial (Nitric-oxide synthase, endothelial)
Seq-ID: P29473 [Bos taurus]
Download:fasta csv
Interaction Network(s): -
External Source(s):
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
NADP or NADPH binding,
FAD binding,
calmodulin binding,
nitric-oxide synthase activity,
FMN binding		 caveola,
cytoskeleton,
Golgi apparatus		 blood coagulation,
oxidation reduction,
anti-apoptosis,
positive regulation of guanylate cyclase activity,
arginine catabolic process,
nitric oxide biosynthetic process,
mitochondrion organization
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 83 VKNWELGSITYDTLCAQSQQD SRC 16123043
LTP
0.16
 - -
0.42
 1Q2O 30.13%
S 116 VLPRKLQTRPSPGPPPAEQLL - 12501214
LTP
0.12
 - -
0.78
 1NSE 33.61%
S 116 VLPRKLQTRPSPGPPPAEQLL - 14593122
LTP
0.12
 - -
0.78
 1NSE 33.61%
T 497 TKGAGITRKKTFKEVANAVKI - 12384459
LTP
0.05
 - -
0.31
 --
T 497 TKGAGITRKKTFKEVANAVKI PKC_alpha 12869534
LTP
0.05
 - -
0.31
 --
T 497 TKGAGITRKKTFKEVANAVKI - 12952971
LTP
0.05
 - -
0.31
 --
T 497 TKGAGITRKKTFKEVANAVKI - 11729179
LTP
0.05
 - -
0.31
 --
S 617 QHKSYKIRFNSVSCSDPLVSS - 12171920
LTP
1.00
 - Flavodoxin_1
0.20
 --
S 617 QHKSYKIRFNSVSCSDPLVSS - 15087285
LTP
1.00
 - Flavodoxin_1
0.20
 --
S 635 VSSWRRKRKESSNTDSAGALG - 12171920
LTP
0.11
 - Flavodoxin_1
0.47
 --
S 635 VSSWRRKRKESSNTDSAGALG - 12384459
LTP
0.11
 - Flavodoxin_1
0.47
 --
S 635 VSSWRRKRKESSNTDSAGALG - 15743275
LTP
0.11
 - Flavodoxin_1
0.47
 --
S 1179 QEVTSRIRTQSFSLQERHLRG AMPK_group 11292821
LTP
0.12
 - -
0.41
 --
S 1179 QEVTSRIRTQSFSLQERHLRG - 12384459
LTP
0.12
 - -
0.41
 --

Substrate: Nitric-oxide synthase, endothelial (Nitric-oxide synthase, endothelial)
Seq-ID: P29474 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
arginine binding,
actin monomer binding,
heme binding,
cadmium ion binding,
NADP or NADPH binding,
FAD binding,
calmodulin binding,
nitric-oxide synthase activity,
tetrahydrobiopterin binding,
FMN binding		 Golgi membrane,
caveola,
cytosol,
cytoskeleton		 regulation of blood vessel size,
positive regulation of vasodilation,
oxidation reduction,
blood vessel remodeling,
regulation of systemic arterial blood pressure by endothelin,
anti-apoptosis,
response to heat,
positive regulation of guanylate cyclase activity,
arginine catabolic process,
negative regulation of muscle hyperplasia,
positive regulation of angiogenesis,
nitric oxide biosynthetic process,
smooth muscle hyperplasia,
endothelial cell migration,
negative regulation of platelet activation,
response to fluid shear stress,
mitochondrion organization
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 81 VKNWEVGSITYDTLSAQAQQD - 18083107
HTP
0.16
 - -
0.51
 1M9M 55.02%
T 495 AKGTGITRKKTFKEVANAVKI - 16126727
LTP
0.05
 - -
0.33
 --
S 615 QHKSYKIRFNSISCSDPLVSS PKB_group 12171920
LTP
0.23
 - Flavodoxin_1
0.19
 --
S 633 VSSWRRKRKESSNTDSAGALG PKA_group 12171920
LTP
0.04
 MOD_PKA_1
 - Flavodoxin_1
0.47
 --
S 1177 QEVTSRIRTQSFSLQERQLRG - 16126727
LTP
0.16
 MOD_PKB_1
 - -
0.41
 --
S 1177 QEVTSRIRTQSFSLQERQLRG PKB_group 10376603
LTP
0.16
 MOD_PKB_1
 - -
0.41
 --
S 1177 QEVTSRIRTQSFSLQERQLRG PKB_group 12446767
LTP
0.16
 MOD_PKB_1
 - -
0.41
 --
S 1177 QEVTSRIRTQSFSLQERQLRG PKB_group 12791703
LTP
0.16
 MOD_PKB_1
 - -
0.41
 --
S 1177 QEVTSRIRTQSFSLQERQLRG PKB_group 16043647
LTP
0.16
 MOD_PKB_1
 - -
0.41
 --
S 1179 VTSRIRTQSFSLQERQLRGAV PKB_group 12501214
LTP
0.08
 MOD_PKB_1
 - -
0.37
 --

Substrate: Nitric-oxide synthase, endothelial (Nitric-oxide synthase, endothelial)
Seq-ID: P70313 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
NADP or NADPH binding,
FAD binding,
calmodulin binding,
nitric-oxide synthase activity,
FMN binding		 caveola,
cytoskeleton,
Golgi apparatus		 regulation of blood vessel size,
lung development,
angiogenesis,
oxidation reduction,
negative regulation of calcium ion transport,
blood vessel remodeling,
lipopolysaccharide-mediated signaling pathway,
regulation of sodium ion transport,
negative regulation of muscle hyperplasia,
positive regulation of angiogenesis,
ovulation from ovarian follicle,
nitric oxide biosynthetic process,
smooth muscle hyperplasia,
negative regulation of hydrolase activity,
negative regulation of potassium ion transport
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 494 AKGAGITRKKTFKEVANAVKI - 16081872
LTP
0.05
 - -
0.29
 - medium
T 1174 RTQEVTSRIRTQSFSLQERQL - 17242355
HTP
0.04
 - -
0.41
 - medium
S 1176 QEVTSRIRTQSFSLQERQLRG - 17242355
HTP
0.16
 - -
0.39
 - medium
S 1176 QEVTSRIRTQSFSLQERQLRG - 16081872
LTP
0.16
 - -
0.39
 - medium

Substrate: Nitric-oxide synthase, endothelial (Nitric-oxide synthase, endothelial)
Seq-ID: Q28969 [Sus scrofa]
Download:fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
NADP or NADPH binding,
FAD binding,
calmodulin binding,
nitric-oxide synthase activity,
FMN binding		 caveola,
cytoskeleton,
Golgi apparatus		 oxidation reduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 497 AKGTGIARKKTFKEVANAVKI - 15333638
LTP
0.03
 - -
0.29
 - low
T 497 AKGTGIARKKTFKEVANAVKI - 11744698
LTP
0.03
 - -
0.29
 - low
S 1179 QEVTSRIRTQSFSLQERHLRG - 15333638
LTP
0.16
 - -
0.42
 - low
S 1179 QEVTSRIRTQSFSLQERHLRG - 11744698
LTP
0.16
 - -
0.42
 - low

Substrate: Nitric-oxide synthase, endothelial (Nitric-oxide synthase, endothelial)
Seq-ID: Q62600 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
NADP or NADPH binding,
FAD binding,
calmodulin binding,
nitric-oxide synthase activity,
FMN binding		 caveola,
cytoskeleton,
nucleolus,
Golgi apparatus,
apical part of cell,
soluble fraction		 oxidation reduction,
response to amino acid stimulus,
response to hypoxia,
response to organic cyclic substance,
response to lead ion,
aging,
response to drug,
response to estradiol stimulus,
signal transduction,
negative regulation of smooth muscle cell proliferation,
response to cytokine stimulus,
nitric oxide biosynthetic process,
response to peptide hormone stimulus,
response to hyperoxia,
response to ethanol,
response to lipoprotein stimulus
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 117 KLQSRPTQGPSPTEQLLGQAR - 15319431
LTP
0.00
 - NO_synthase
0.78
 - low
T 494 AKGTGITRKKTFKEVANAVKI - 15319431
LTP
0.05
 - -
0.32
 - low
T 494 AKGTGITRKKTFKEVANAVKI AMPK_group 10025949
LTP
0.05
 - -
0.32
 - low
T 494 AKGTGITRKKTFKEVANAVKI - 16244499
LTP
0.05
 - -
0.32
 - low
S 632 VSSWRRKRKESSNTDSAGALG - 15383397
LTP
0.05
 - Flavodoxin_1
0.47
 - low
S 632 VSSWRRKRKESSNTDSAGALG - 14993198
LTP
0.05
 - Flavodoxin_1
0.47
 - low
S 1176 QEVTSRIRTQSFSLQERQLRG - 15319431
LTP
0.16
 - -
0.40
 - low
S 1176 QEVTSRIRTQSFSLQERQLRG AMPK_group 10025949
LTP
0.16
 - -
0.40
 - low
S 1176 QEVTSRIRTQSFSLQERQLRG - 16244499
LTP
0.16
 - -
0.40
 - low

Substrate: Nitric-oxide synthase, endothelial (Nitric-oxide synthase, endothelial)
Seq-ID: Q6Y5E2 [Oryctolagus cuniculus]
Download:fasta csv
Interaction Network(s):
External Source(s):
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
NADP or NADPH binding,
FAD binding,
calmodulin binding,
FMN binding		 oxidation reduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 1183 QEVTSRIRTQSFSLQERQLRG - 15383526
LTP
0.12
 - -
0.39
 - low
S 1183 QEVTSRIRTQSFSLQERQLRG - 12193462
LTP
0.12
 - -
0.39
 - low

Valid HTML 4.01 Transitional